Xanax or Alprazolam is a panic and anxiety disorder treatment medicines that belongs to the benzodiazepine group. It works by affecting the central nervous system and blocks the anxiety and panic sensations in between the nerves and the brains. It also boosts the effect of gamma-amino butyric acid (GABA), a natural brain chemical that enhances the calming effect in the brain. People are recommended to purchase Xanax from online Xanax drugstores in order to get hold of quality pills legally without any hassle.
Clinical trial of long term Xanax usage in Anxiety Disorder treatment:
This clinical trial has been conducted upon two groups of patients. One group consisted of patients who were given 4 mg/day of Xanax for four weeks and the other group consisted of patients who were given 10 mg/day for up to ten weeks. The study concluded that more people, who were given the higher dose and for a prolonged period, reported for treatment emergent symptoms and medical intervention was required.
Clinical trial for the safety and efficacy of Xanax:
In another clinical trial conducted on 631 random patients meeting the Diagnostic and Statistical Manual of Mental Disorders criteria as per the Third and Fourth Edition, the safety and efficacy of Xanax in comparison to other comparator benzodiazepines was determined. No results succeeded in proving Xanax as safer and better in increasing the panic attack frequency, proportion of patients, who have been freed from panic attacks and Hamilton Anxiety Rating Scale score improvement.
Clinical trial for Xanax sublingual tablet efficacy in acute phase of panic disorder treatment:
2-5% of the general population is affected with panic disorder. A clinical trial was conducted to study the efficacy of alprazolam sublingual tablets in treating acute phase panic disorder. The trail results indicated that the alprazolam sublingual tablets had higher advantages, whereas the efficacy of sublingual and general pills had no difference. The inference was drawn on the basis of the outcomes of these factors –
- Hamilton Rating Scale for Anxiety (HAM-A)
- Clinical Global Impressions (CGI-S/CGI-I)
- Psychological General Well-Being Index (PGWBI)
- Arizona Sexual Experiences Scale (ASEX)
- Panic Disorder Severity Scale (PDSS)
- Patient Global Impression (PGI).
Different clinical trials have different results. However, all indicate that upon long term usage and upon consumption of higher level dosage, dependency, habit and addiction might occur. Hence, the prescribed dosage must always be followed and in case any side effects are encountered and identified, it must be informed to the doctor. The dosage must be determined as per the individual condition of the patient and during this, the health conditions must be taken into account. The clinical trial reports help the doctors in going through latest studies of Xanax.
However, it must be taken as per the prescribed dosage and higher dosage can lead to addiction. In fact, prolonged use and dependency on the medicine can be highly habit forming and one might experience serious withdrawal symptoms, upon abrupt and sudden quitting of this drug. Many clinical trials have been conducted in order to determine the effects of the pill in treating anxiety and panic disorder.